Heat shock proteins as diagnostic markers for hepatocellular carcinoma: a novel approach

نویسندگان

چکیده

Hepatocellular carcinoma (HCC) is a malignant tumor of the liver. Heat shock proteins play their part in response to cellular stress. They are overexpressed many forms cancers where they shield cells from stressful environment thus contributing poor prognosis and treatment resistance. HSP 27, heat protein mostly associated with Hepatitis induced hepatocellular cancer, inhibits apoptosis 70 along 90 contributes metastasis. count higher comparison normal it related size, stage vessel invasion while 20 regresses as progresses. Considering all these factors, differentiation HCC other liver pathologies becomes much easier at an early stage. Early diagnosis important timely prompt can decrease mortality HCC. On grounds useful characteristics like detection accuracy detailing metastasis our Review suggests that HSPs also have therapeutic potential targeting specific markers help patients diagnosed innovation management cure Extensive research exploring Shock Proteins Carcinoma was done on search engines such Science Direct, OVID, Google Scholar, PubMed, MEDLINE. Articles published languages than English were considered. Data solely conference or meeting proceedings, websites, books not included.

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ژورنال

عنوان ژورنال: Gastroenterology & hepatology

سال: 2023

ISSN: ['2373-6372']

DOI: https://doi.org/10.15406/ghoa.2023.14.00535